Annamaria Biroccio | Molecular Biology | Best Researcher Award

Dr. Annamaria Biroccio | Molecular Biology | Best Researcher Award

IRCCS-Regina Elena National Cancer Institute | Italy

Dr. Annamaria Biroccio, PhD (Microbiology, University of Messina) is a Senior Investigator at the Regina Elena National Cancer Institute (IRE-IFO), Rome, with over two decades of experience in cancer molecular biology and telomere research. Her work focuses on elucidating the mechanisms regulating telomere function and their implications in cancer progression, alongside developing pharmacological strategies targeting telomeres for anticancer therapy. She has published extensively in high-impact journals, contributing over 115 peer-reviewed papers on telomere biology, DNA damage response, and targeted therapies. According to her CV, Dr. Biroccio holds an H-index of 44, reflecting substantial influence in the field, with more than 6124 citations across her publications. Her research leadership is underscored by principal investigator roles in major national and international grants, including AIRC, CNR, and EU FP7 programs. She is also co-owner of two patents related to telomere-targeting therapeutics for triple-negative breast cancer. In recognition of her contributions, she has received multiple awards such as the Mascia Brunelli Award and Young Investigator Award. Beyond research, Dr. Biroccio has significantly contributed to scientific training as a tutor for numerous national fellowship programs and serves on editorial boards of prominent cancer research journals

Featured Publications

Dinami, R., Petti, E., Ostano, P., Iachettini, S., Rizzo, A., Maresca, C., Zizza, P., Di Vito, S., Porru, M., D’Angelo, C., Sibilio, P., De Nicola, F., Russo, R., Di Benedetto, A., Palange, A., Fanciulli, M., Chambery, A., Gilson, E., & Biroccio, A. (2025). Multi-omics analyses integration reveals a novel TRF2–miR-181a-5p–S100A10 regulatory axis in colon cancer. Cellular and Molecular Biology Letters, 30(1), 121.

Petti, E., Di Vito, S., Dinami, R., Porru, M., Marchesi, S., Lohuis, J., Zizza, P., Iachettini, S., Salvati, E., D’Angelo, C., Rizzo, A., Maresca, C., Ascione, F., Di Benedetto, A., Buglioni, S., Sacconi, A., Ostano, P., Li, Q., Stoppacciaro, A., Leonetti, C., van Rheenen, J., Maiuri, P., Scita, G., & Biroccio, A. (2025). TRF2 interaction with nuclear envelope is required for cell polarization and metastasis in triple-negative breast cancer. Cell Death & Disease, 16(1), 224.

Pirota, V., Iachettini, S., Platella, C., Zizza, P., Fracchioni, G., Di Vito, S., Carachino, A., Battistini, F., Orozco, M., Freccero, M., Biroccio, A., & Doria, F. (2025). Naphthalene diimide–naphthalimide dyads promote telomere damage by selectively targeting multimeric G-quadruplexes. Nucleic Acids Research, 53(7), gkaf301.

Russomanno, P., Zizza, P., Cerofolini, L., D’Aria, F., Iachettini, S., Di Vito, S., Amato, J., Fragai, M., Pagano, B., & Biroccio, A. (2025). Expanding the functions of KHSRP protein: Insights into DNA G-quadruplex binding. Advanced Science, 12(8), e2410086.

Pirota, V., Salvati, E., Risoldi, C., Manoli, F., Rizzo, A., Zizza, P., Biroccio, A., Freccero, M., & Manet, I. (2025). Core-extended naphthalene diimide dyads as light-up probes with targeted cytotoxicity toward tumor cells. Biomolecules, 15(2), 311.

Betul Akdal Dolek | Global Health | Best Researcher Award

Dr. Betul Akdal Dolek | Global Health | Best Researcher Award

Ankara Bilkent City Hospital | Turkey

Dr. Betul Akdal Dolek is a radiologist at Ankara Bilkent City Hospital, specializing in abdominal imaging, diffusion-weighted MRI, quantitative CT, and oncologic imaging. She obtained her medical degree from Ankara University and completed her radiology residency at Ankara Numune Training and Research Hospital. With an h-index of 6, Dr. Dolek’s scholarly record includes 11 SCI/Scopus-indexed publications and numerous conference presentations. Her work has garnered over 160 citations (as per Google Scholar).  She has significantly contributed to quantitative MRI and CT research, focusing on imaging biomarkers for metabolic, inflammatory, and oncologic diseases. Notably, she participated in the COST Action “A Comprehensive Network Against Brain Cancer”, advancing biomarker protocols for glioblastoma imaging. Her publications cover diverse radiologic fields, including the reliability of O-RADS MRI scoring, coronary calcium quantification, and perfusion imaging in acute kidney injury. Dr. Dolek has also authored the book “Hard Decisions in Intensive Care Unit” and serves as a reviewer in national research committees. Actively collaborating in multidisciplinary radiology-oncology teams and invited as a speaker at ESR and TMRD congresses, she continues to enhance diagnostic precision and innovation in modern radiology practice.

Featured Publications

Akkurt Acar, D., Cilengir, A. H., Balaban, M., Camur, E., Akdal Dolek, B., & Isıksalan Ozbulbul, N. Diaphragmatic crus indentation to the renal artery: Is it a new etiology for renovascular hypertension in adults? Northwestern Medical Journal.

Kılıckap, G., Akdal Dolek, B., Kaya, S., & Cevik, N. İ. Reliability, reproducibility, and potential pitfalls of the O-RADS scoring with non-dynamic MRI. Acta Radiologica.

Akdal Dolek, B., Sozmen Ciliz, D., Ozdemir, N., Ozet, G., & Duran, S. Comparative analysis of whole-body diffusion-weighted imaging and PET/CT in metastasis detection: A prospective study. Cureus, 16(11), e74756.

Kılıçkap, G., Akdal Dolek, B., Cevik, N. İ., Bahadır, G. K., Tekdemir, H., & Vural, M. Time difference for the presence of coronary calcium in those with and without coronary risk factors and statin use. Acta Cardiologica, 79(7), 787–795.

Vural, M., Akdal Dolek, B., Kılıckap, G., Bahadır, G. K., & Gunes, Y. C. Epicardial adipose tissue (EAT) thickness on non-gated chest CT as an alternative to EAT volume on cardiac CT. Acta Radiologica, 65(6),