Dr. Irina Primac | Nuclear Medicine | Best Researcher Award

Belgian Nucler Research Center SCK CEN | Belgium

Dr. Irina Primac, PhD, is an accomplished cancer biologist and radiopharmaceutical researcher, currently serving as Head of the Radiobiology Unit at the Belgian Nuclear Research Centre (SCK CEN). She leads a multidisciplinary team focusing on radiotheranostics and tumor microenvironment research, integrating molecular radiobiology with translational cancer therapy. With an H-index of 10, over 744 citations, and more than 25 peer-reviewed publications, Dr. Primac’s research demonstrates a strong impact on the fields of cancer radiotherapy, epigenetics, and radiopharmaceutical innovation. Her high-impact papers include contributions in Nature Reviews Clinical Oncology, Cell, and the Journal of Clinical Investigation, underscoring her international recognition. She has been awarded multiple EU-funded research grants such as Thera4Care and Accelerate.EU, leading preclinical work on FAPI-based radioligands for metastatic and triple-negative breast cancers. A recipient of several national and international research prizes and fellowships, Dr. Primac actively contributes to European cancer research initiatives and editorial boards. Her scientific vision centers on advancing precision oncology through next-generation theranostic platforms, bridging laboratory innovation with patient-centered cancer care.

Profiles: Scopus | Orcid

Featured Publications

Rajan, N., Primac, I., Etlioglu, E., Debruyne, L., Janssen, A., Sallam, M., Tabury, K., Quintens, R., Tjalma, W., & Benotmane, M. A. Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow-up biomarkers for breast cancer. Molecular Oncology.

Florit, A., de Koster, E. J., Sassano, S., Alic, L., Pisano, G., van Velden, F. H. P., Annunziata, S., Primac, I., Ruggiero, M. R., Müller, C., & others. Head-to-head comparison of fibroblast activation protein inhibitors (FAPI) radiopharmaceuticals and [18F]FDG in gynaecological malignancies: Systematic literature review and meta-analysis. European Journal of Nuclear Medicine and Molecular Imaging.

Quarto, G., Li Greci, A., Bizet, M., Penning, A., Primac, I., Murisier, F., Garcia-Martinez, L., Borges, R. L., Gao, Q., Cingaram, P. K. R., & others. Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation. Cell.

Penning, A., Wang, K., Célérier, M., Collignon, E., Primac, I., Van der Linden, L., Bizet, M., Calonne, E., Hassabi, B., Hubert, C., & others. m3C is a mitochondrial mRNA modification which promotes tumor progression. bioRxiv.

Primac, I., Penning, A., & Fuks, F. Cancer epitranscriptomics in a nutshell. Current Opinion in Genetics and Development, 75, 101924.

Irina Primac | Nuclear Medicine | Best Researcher Award

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